UNIT 1:
Introduction of carbohydrate
UNIT 2:
UNIT 3:
Beta oxidation of fatty acids
Formation and utilisation of ketone bodies
De novo synthesis of fatty acid
Biological significance of cholesterol
Disorders of Lipid metabolism
General reaction of Amino acid metabolism
Urea cycle and its disorders
Catabolism of phenylalanine and tyrosine and their metabolic disorders
Synthesis and significance of biological substances; 5-HT, melatonin,
Catabolism of heme; hyperbilirubinemia and jaundice
UNIT 4:
Biosynthesis of purine nucleotides
Catabolism of purine nucleotides
Organization of mammalian genome
Structure of DNA and its functions
Structure of RNA and its functions
DNA replication (semi conservative model)
Transcription or RNA synthesis
Genetic code, Translation or Protein synthesis and inhibitors
UNIT 5:
Introduction, properties, nomenclature
Enzyme inhibitors with examples
Regulation of enzymes: enzyme induction and repression, allosteric enzymes regulation
Coenzymes –Structure and biochemical functions
Therapeutic and diagnostic applications of enzymes and isoenzymes
