Introduction, definitions, Homeostasis, Components and Types of Feedback systems, Causes of cellular injury,Pathogenesis (Cell membrane damage, Mitochondrial damage, Ribosome damage, Nuclear damage),Morphology of cell injury – Adaptive changes (Atrophy, Hypertrophy, hyperplasia, Metaplasia, Dysplasia),Cell swelling, Intra cellular accumulation, Calcification, Enzyme leakage and Cell Death Acidosis &Alkalosis,Electrolyte imbalance. Inflammation: Introduction, Clinical signs of inflammation, Different types of Inflammation,Mechanism of Inflammation – Alteration in vascular permeability and blood flow, migration of WBC’s,Mediators of inflammation,Basic principles of wound healing in the skin,Pathophysiology of Atherosclerosis

Cardiovascular System: Hypertension, congestive heart failure, ischemic heart disease (angina,myocardial infarction, atherosclerosis and arteriosclerosis) Respiratory system:Asthma, Chronic obstructive airways diseases. Renal system:Acute and chronic renal failu

Haematological Diseases: Iron deficiency, megaloblastic anemia (Vit B12 and folic acid), sickle cell anemia, thalasemia, hereditary acquired anemia, hemophilia Endocrine system: Diabetes, thyroid diseases, disorders of sex hormones Nervous system: Epilepsy, Parkinson’s disease, stroke, psychiatric disorders: depression, schizophrenia and Alzheimer’s disease. Gastrointestinal system: Peptic Ulcer

Inflammatory bowel diseases, jaundice, hepatitis (A,B,C,D,E,F) alcoholic liver disease. Disease of bones and joints: Rheumatoid arthritis, osteoporosis and gout Principles of cancer: classification, etiology and pathogenesis of cancer

Infectious diseases:Meningitis,Typhoid, Leprosy, Tuberculosis Urinary tract infections Sexually transmitted diseases:AIDS, Syphilis, Gonorrhea