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ANTI HYPERLIPIDEMIC DRUGS

“Discuss the Classification, Mechanism of Action, Therapeutic Uses, and Adverse Effects of Antihyperlipidemic Drugs” Instructions for 25 -50 Students: Write a detailed assignment (800–1200 words) covering the following points: Classification of antihyperlipidemic drugs with suitable examples. Detailed mechanism of action of at least four major classes (Statins, Fibrates, Niacin, Bile acid sequestrants, Cholesterol absorption inhibitors, PCSK9 inhibitors). Clinical uses of different classes in hypercholesterolemia, hypertriglyceridemia, mixed dyslipidemia. Adverse effects, contraindications, and precautions of major drug groups. Recent advances in lipid-lowering therapy (PCSK9 inhibitors, Inclisiran, Bempedoic acid—basic intro). Rational drug selection and combination therapy in dyslipidemia. Include tables, diagrams, flowcharts, or mind maps to improve presentation. Add references using APA or Vancouver format. 📊 Rubrics for Evaluation (Total: 20 Marks) Criteria Description Marks Content Accuracy & Depth Completeness in classification, MOA, therapeutic uses, adverse effects, and combination therapy. 6 marks Mechanism of Action (Detail & Clarity) Explanation of MOA with diagrams/flowcharts; clarity of pharmacological process. 4 marks Organization & Structure Logical flow, headings, subheadings, introduction, and conclusion. 3 marks Critical Thinking / Application Discussion on rational selection, special patient considerations, recent advances. 3 marks Presentation & Formatting Grammar, neatness, readability, diagrams, tables, correct formatting. 2 marks References Authentic textbooks/journals with proper citation (APA/Vancouver). 2 mark

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ANTI ANGINAL DRUGS

“Explain the Classification, Mechanism of Action, Therapeutic Uses, and Adverse Effects of Antianginal Drugs” Instructions for 51-75 Students: Prepare an assignment (800–1200 words) covering the following: Classification of antianginal drugs (Nitrates, Beta blockers, Calcium channel blockers, Potassium channel openers, Ranolazine, Ivabradine, etc.). Detailed mechanism of action of the major classes (with diagrams/flowcharts). Types of angina (Stable, Unstable, Variant) and the drug of choice for each type. Clinical uses, dosage concepts (basic), and therapeutic rationale. Adverse effects, contraindications, and precautions. Comparison between drug classes (e.g., nitrates vs. CCBs vs. beta blockers). Rational combination therapy in angina. Add tables, diagrams, mind maps, and references (APA/Vancouver). 📊 Rubrics for Evaluation (Total: 20 Marks) Criteria Description Marks Content Accuracy & Depth Correct and complete coverage of classification, MOA, uses, angina types, and adverse effects. 6 marks Mechanism of Action (Detail & Clarity) Clear MOA explanation with diagrams/flowcharts; logical pharmacological insight. 4 marks Organization & Structure Proper headings, sequencing, introduction, and conclusion. 3 marks Application / Critical Thinking Therapeutic rationale, drug selection for types of angina, and combination therapy. 3 marks Presentation & Formatting Neatness, grammar, tables, diagrams, clarity, proper formatting. 2 marks References Authentic and correctly formatted citations (APA/Vancouver). 2 marks

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ANTI ARRYTHMIC DRUGS

“Explain the Classification, Mechanism of Action, Therapeutic Uses, and Adverse Effects of Antiarrhythmic Drugs” Instructions for 76-100 Students: Prepare a detailed assignment (800–1200 words) that includes: Classification of antiarrhythmic drugs based on Vaughan–Williams classification (Class I–IV) and newer agents (e.g., Adenosine, Digoxin, Ivabradine). Detailed mechanism of action of major drug classes (Class I subtypes, Class II, Class III, Class IV). Electrophysiology of cardiac action potential (brief explanation with diagram). Therapeutic uses—drug of choice for different arrhythmias (AF, atrial flutter, ventricular tachycardia, PSVT, etc.). Adverse effects & contraindications of each class. Comparison of drugs/classes (e.g., Amiodarone vs. Sotalol, Class I subclasses). Recent advances (Dronedarone, Vernakalant—brief overview). Include tables, diagrams, flowcharts, and references (APA or Vancouver format). 📊 Rubrics for Evaluation (Total: 20 Marks) Criteria Description Marks Content Accuracy & Completeness Correct, detailed coverage of classification, electrophysiology, MOA, uses, and adverse effects. 6 marks Mechanism of Action (Depth & Clarity) Clear explanation with diagrams/flowcharts; accurate relation to cardiac action potential. 4 marks Organization & Structure Logical flow with headings, subheadings, introduction, and conclusion. 3 marks Critical Thinking / Application Proper drug selection for specific arrhythmias; comparison of classes; therapeutic reasoning. 3 marks Presentation & Formatting Neatness, grammar, formatting, tables/illustrations/diagrams. 2 marks References Use of credible textbooks/journals with correct citation format. 2 marks

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ANTI HYPERTENSIVE DRUGS

“Explain the Classification, Mechanism of Action, and Clinical Use of Antihypertensive Drugs” Instructions for 1-25 Students: Write a structured assignment (800–1200 words) covering the following: Classification of antihypertensive drugs (with examples). Mechanism of action of any four major classes (e.g., ACE inhibitors, ARBs, CCBs, Beta blockers, Diuretics). Drug selection in special populations (diabetes, pregnancy, renal disease, elderly). Adverse effects and contraindications of major classes. Rational combination therapy in hypertension. Include diagrams/flowcharts/mind map wherever needed. Provide latest clinical guidelines (JNC-8, ACC/AHA—briefly). Add references (APA or Vancouver format). 📊 Rubrics for Evaluation (Total: 20 Marks) Criteria Description Marks Content Accuracy & Depth Correct, complete explanation of classification, mechanism, uses, adverse effects & special considerations. Shows understanding and relevance to Unit-1. 6 marks Organization & Structure Clear introduction, logical flow, headings/subheadings, conclusion. Smooth transitions between sections. 3 marks Mechanism of Action (Detail & Clarity) Well-explained MOA of selected classes with diagrams/flowcharts or simple illustrations. 4 marks Critical Thinking / Application Discussion of rational drug selection, special populations, and combination therapy. 3 marks Presentation & Formatting Neatness, readability, grammar, proper formatting, tables/figures, reference style. 2 marks References Use of authentic textbooks/journals with correct citation format. 2 marks